B Symptoms - Description and Nomenclature

Description and Nomenclature

B symptoms are so called because Ann Arbor staging of lymphomas includes both a number (I-IV) and a letter (A or B);. "A" indicates the absence of systemic symptoms, while "B" indicates their presence.

B symptoms include:

  • Fever greater than 38°C. Pel-Ebstein fever, the classic intermittent fever associated with Hodgkin disease, occurs at variable intervals of days to weeks and lasts for 1–2 weeks before resolving. However, fever associated with lymphoma can follow virtually any pattern.
  • Drenching sweats, especially at night.
  • Unintentional weight loss of >10% of normal body weight over a period of 6 months or less.

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