R. Gordon Wasson has posited that the plant known as pipiltzintzintli is in fact Salvia divinorum. It's not entirely known whether or not this plant was used by the Aztecs as a psychotropic, but Jonathan Ott (1996) argues that although there are competing species for the identification of pipiltzintzintli, Salvia divinorum is probably the "best bet." There are references to use of pipiltzintzintli in Spanish arrest records from the conquest, as well as a reference to the mixing of ololiuqui with pipiltzintzintli.
Contemporaneously, the Mazatec, meaning "people of the deer" in Nahuatl, from the Oaxaca region of Mexico utilize Salvia divinorum when Psilocybe spp. mushrooms are not readily available. They chew and swallow the leaves of fresh salvia to enter into a shamanic state of consciousness. The Mazatec use the plant in both divination and healing ceremonies, perhaps as the Aztecs did 500 years ago. Modern users of Salvia have adapted the traditional method, forgoing the swallowing of juices due to Salvinorin A being readily absorbed by the mucous membranes of the mouth.
Read more about this topic: Aztec Use Of Entheogens