Ayla may refer to:
- Ayla (name), a Hebrew name meaning "oak tree" and a modern Turkish name meaning "Halo of light around the moon and in some cases the sun."
- Ayla (Earth's Children), protagonist of Jean M. Auel's popular 1984 novel The Clan of the Cave Bear and its sequels
- Ayla (Chrono Trigger), player character in the video game Chrono Trigger
- Ayla (producer), German trance musician
- Ayla Brown, former American Idol contestant
- Ayla Kell, American Actress
- Ayla Ranzz, the fictional comic book character in the DC Universe
- Ayla (city), Ayla, the medieval city on the Red Sea