Atypical Teratoid Rhabdoid Tumor - Pathology - Histology

Histology

Histology is the study of the microscopic anatomy of cells and tissues of plants and animals. It is performed by examining a thin slice of tissue under a light microscope. The tumor histopathology is jumbled small and large cells. The tissue of this tumor contains many different types of cells including the rhabdoid cells, large spindled cell, epithelial and mesenchymal cells and areas resembling primitive neuroectodermal tumor (PNET). As much as 70% of the tumor may be made up of PNET-like cells. Ultrastructure characteristic whorls of intermediate filaments in the rhabdoid tumors (as with rhabdoid tumors in any area of the body). Ho and associates found sickle-shaped embracing cells, previously unreported, in all of 11 cases of AT/RT.

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