Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include mutations (which can destroy the gene to build up the organ), poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, excessive amount of apoptosis of cells, and disuse or lack of exercise or disease intrinsic to the tissue itself. Hormonal and nerve inputs that maintain an organ or body part are referred to as trophic in medical practice ('trophic" is an adjective that can be paired with various nouns). Trophic describes the trophic condition of tissue. A diminished muscular trophic is designated as atrophy.
Atrophy is the general physiological process of reabsorption and breakdown of tissues, involving apoptosis on a cellular level. When it occurs as a result of disease or loss of trophic support due to other disease, it is termed pathological atrophy, although it can be a part of normal body development and homeostasis as well.
Read more about Atrophy: Research
Famous quotes containing the word atrophy:
“The author’s conviction on this day of New Year is that music begins to atrophy when it departs too far from the dance; that poetry begins to atrophy when it gets too far from music; but this must not be taken as implying that all good music is dance music or all poetry lyric. Bach and Mozart are never too far from physical movement.”
—Ezra Pound (1885–1972)
“The three great problems of this century, the degradation of man in the proletariat, the subjection of women through hunger, the atrophy of the child by darkness.”
—Victor Hugo (1802–1885)
“Unless they are immediate victims, the majority of mankind behaves as if war was an act of God which could not be prevented; or they behave as if war elsewhere was none of their business. It would be a bitter cosmic joke if we destroy ourselves due to atrophy of the imagination.”
—Martha Gellhorn (b. 1908)