Structure
Located within the mitochondria, ATP synthase consists of 2 regions
- the FO portion is within the membrane.
- The F1 portion of the ATP synthase is above the membrane, inside the matrix of the mitochondria.
The nomenclature of the enzyme suffers from a long history. The F1 fraction derives its name from the term "Fraction 1" and FO (written as a subscript letter "o", not "zero") derives its name from being the oligomycin binding fraction. Oligomycin, an antibiotic, is able to inhibit the FO unit of ATP synthase.
These functional regions consist of different protein subunits - refer to tables.
Read more about this topic: ATP Synthase
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