Artificial Microfluidic Skin For in Vitro Perspiration Simulation and Testing
An artificial skin has also been recently demonstrated at the University of Cincinnati for in-vitro sweat simulation and testing, capable of skin-like texture, wetting, sweat pore-density, and sweat rates. The sweat simulator employs a simple bi-layer membrane design to resolve all drawbacks associated with use of commercial membranes. A bottom 0.2 µm track etched polycarbonate membrane layer provides flow-rate control by creating a pressure drop and therefore a constant sweat flow. A top photo-curable layer provides skin-like features such as sweat pore density, hydrophobicity, and wetting hysteresis. Key capabilities of this sweat simulator include: constant ‘sweat’ rate density without bubble-point variation even down to ~1 L/hr/m2; replication of the 2 pores/mm2 pore-density and the ~50 µm texture of human skin; simple gravity-fed flow control; low-cost and disposable construction.
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