Artificial Skin - Artificial Microfluidic Skin For in Vitro Perspiration Simulation and Testing

Artificial Microfluidic Skin For in Vitro Perspiration Simulation and Testing

An artificial skin has also been recently demonstrated at the University of Cincinnati for in-vitro sweat simulation and testing, capable of skin-like texture, wetting, sweat pore-density, and sweat rates. The sweat simulator employs a simple bi-layer membrane design to resolve all drawbacks associated with use of commercial membranes. A bottom 0.2 µm track etched polycarbonate membrane layer provides flow-rate control by creating a pressure drop and therefore a constant sweat flow. A top photo-curable layer provides skin-like features such as sweat pore density, hydrophobicity, and wetting hysteresis. Key capabilities of this sweat simulator include: constant ‘sweat’ rate density without bubble-point variation even down to ~1 L/hr/m2; replication of the 2 pores/mm2 pore-density and the ~50 µm texture of human skin; simple gravity-fed flow control; low-cost and disposable construction.

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