Aromatic-ring-hydroxylating Dioxygenases - Biochemical Classification

Biochemical Classification

EC 1.14.12.3 benzene 1,2-dioxygenase

benzene + NADH + H+ + O2 = cis-cyclohexa-3,5-diene-1,2-diol + NAD+

EC 1.14.12.7 phthalate 4,5-dioxygenase

phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+

EC 1.14.12.8 4-sulfobenzoate 3,4-dioxygenase

4-sulfobenzoate + NADH + H+ + O2 = 3,4-dihydroxybenzoate + sulfite + NAD+

EC 1.14.12.9 4-chlorophenylacetate 3,4-dioxygenase

4-chlorophenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+

EC 1.14.12.10 benzoate 1,2-dioxygenase

benzoate + NADH + H+ + O2 = 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+

EC 1.14.12.11 toluene dioxygenase

toluene + NADH + H+ + O2 = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+

EC 1.14.12.12 naphthalene 1,2-dioxygenase

naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+

EC 1.14.12.15 terephthalate 1,2-dioxygenase

terephthalate + NADH + H+ + O2 = (1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate + NAD+

EC 1.14.12.18 biphenyl 2,3-dioxygenase

biphenyl + NADH + H+ + O2 = (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+

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