Arlen may refer to:
- Places
- Arlen, Texas, a fictional town in the United States, where the animated series King of the Hill is set
- People
- Harold Arlen, an American musical composer
- Michael Arlen, an Armenian novelist and short story writer
- Richard Arlen, an American actor
- Arlen Erdahl (born 1931), an American politician
- Arlen Gargagliano, an American writer and chef
- Arlen Harris (born 1980), an American football player
- Arlen Lancaster, chief of the United States Department of Agriculture
- Arlen Ness, an American motorcycle designer
- Arlen Roth (born 1952), an American guitarist
- Arlen Siu (died 1972), a Chinese-Nicaraguan writer
- Arlen Specter (1930–2012), an American politician
- Arlen Thompson, drummer of the indie rock group Wolf Parade