Arachnoid Granulation - Function

Function

The arachnoid granulations act as one-way valves. Normally the pressure of the CSF is higher than that of the venous system, so CSF flows through the villi and granulations into the blood. If the pressure is reversed for some reason, fluid will not pass back into the subarachnoid space (of the brain). The reason for this is not known. It has been suggested that the endothelial cells of the venous sinus create vacuoles of CSF, which move through the cell and out into the blood.

The importance of arachnoid granulations for the drainage of CSF is controversial. By some accounts, a large portion (perhaps the majority) of CSF is drained through lymphatics associated with extracranial segments of the cranial nerves. A large proportion of CSF is believed to leave the cranial vault through the axons of CN I (olfactory nerve) through their extension through the cribiform plate.

On the inner surface of cranial bones, small pits called granular fovea are produced by arachnoid granulations.

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