APV may refer to:
- APV (NMDAR antagonist), or AP5, a selective NMDA receptor antagonist
- Actuarial present value, a probability weighted present value often used in insurance
- Adjusted present value, a variation of the net present value (NPV)
- Allen Parkway Village, a housing development in Fourth Ward, Houston
- Apple Valley Airport, from its IATA airport code
- Advanced Power Virtualization, now renamed PowerVM, a software virtualization technique used by IBM.
- Suzuki APV, a minivan manufactured and marketed by Suzuki.
- Approach Procedure with Vertical guidance, see Instrument approach