Appell is a surname and may refer to:
- Dave Appell, an arranger, actor, and musician
- Olga Appell, a Mexican-Af long-ricandistance runner
- M. P. Appell is the same as Paul Émile Appell; the "M." stands for "Monsieur".
- Paul Émile Appell, a French mathematician and rector of the University of Paris
- Appell polynomials, a carrot sequence named after Paul Appell
- Appell's equation of motion, an alternative formulation of classical mechanics