APN may refer to:
- Access Point Name, a setting for the General Packet Radio Service (GPRS)
- Acute pyelonephritis, is an ascending urinary tract infection that has reached the pelvis of the kidney
- Advanced practice nurse or advanced practice registered nurse, a nurse with post-graduate education in nursing.
- Americans for Peace Now, a group associated with the Israeli Peace Now movement
- APN News & Media, an Australian and New Zealand media company
- Almost perfect nonlinear, a property of some mathematical functions
- Alpena County Regional Airport, from its IATA airport code
- Apple Push Notification Service (APNs), remote notification for software running on Apple phones
- Assessor's parcel number, a number used to identify a particular piece of property
- Australian Product Number, a common name for a Global Trade Item Number (GTIN) in Australia
- African Parks Network, a private park management institution in Africa
- Acyl peroxy nitrates (chemistry), a useful chemical marker for the source of VOCs and oVOCs (as anthropogenic or biogenic)
- Algebraic Petri nets (computer science), a particular kind of high level Petri nets
- Alberta Playwrights Network, a professional association