Apical Ectodermal Ridge

Apical Ectodermal Ridge

Apical Ectodermal Ridge (AER)

The apical ectodermal ridge (AER) is a structure that forms from the ectodermal cells at the distal end of each limb bud and acts as a major signaling center to ensure proper development of a limb. After the limb bud induces AER formation, the AER and limb mesenchyme – including the zone of polarizing activity (ZPA) - continue to communicate with each other to direct further limb development.

Read more about Apical Ectodermal RidgeFormation, Roles, Relationship Between Hox Gene Expression and Limb Patterning, Relevant Experiments, Relevant Molecules

Other articles related to "apical ectodermal ridge":

Apical Ectodermal Ridge - Relevant Molecules
... FGF10 expression activates secretion of WNT3A, which acts upon the apical ectodermal ridge (AER) and induces FGF8 expression ... FGF8 = Secreted by the apical ectodermal ridge cells ...

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