AP4M1

AP4M1

Identifiers Symbols AP4M1; CPSQ3; MU-4; MU-ARP2; SPG50 External IDs OMIM: 602296 MGI: 1337063 HomoloGene: 3467 GeneCards: AP4M1 Gene

Gene Ontology
Molecular function	• transporter activity
Cellular component	• Golgi trans cisterna • coated pit • AP-type membrane coat adaptor complex • clathrin adaptor complex
Biological process	• intracellular protein transport • vesicle-mediated transport
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9179 11781 Ensembl ENSG00000221838 ENSMUSG00000019518 UniProt O00189 Q9JKC7 RefSeq (mRNA) NM_004722 NM_021392 RefSeq (protein) NP_004713 NP_067367 Location (UCSC) Chr 7:
99.7 – 99.71 Mb Chr 5:
138.17 – 138.18 Mb PubMed search

AP-4 complex subunit mu-1 is a protein that in humans is encoded by the AP4M1 gene.

This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.