AP-7 (drug)

AP-7 (drug)

AP-7 is a selective NMDA receptor (NMDAR) antagonist that competitively inhibits the glutamate binding site and thus activation of NMDAR. It has anticonvulsant effects.

AP-7 functions specifically as a NMDA recognition site blocker, in contrast with 7c-KYNA which acts as a glycine site modulation blocker.