Anti-ganglioside Antibodies - Triggering Agents - Coeliac Disease

Coeliac Disease

Antibodies to ganglioside are found to be elevated in coeliac disease. Recent studies show that gliadin can cross-link to gangliosides in a transglutaminase independent manner, indicating that gliadin specific T-cell could present these antigens to the immune system.

Read more about this topic:  Anti-ganglioside Antibodies, Triggering Agents

Other articles related to "coeliac disease, disease, coeliac":

HLA A1-B8-DR3-DQ2 - Importance To Medicine - In Coeliac Disease & Dermatitis Herpetiformis
... the association with HLA-A1 and B8 was identified for coeliac disease in 1973 and dermatitis herpetiformis in 1976 ... Because of the haplotype it became possible to identify the genetic risk even though disease causing genes, a DQ2 haplotype, was 1.3 million nucleotides away ... Further information HLA-DQ2 in coeliac disease and HLA-DQ2.5 in gluten immunochemistry Aside from the highly studied link between DQ2.5 and coeliac disease, there are additional risk factors on the B8DQ2 ...
HLA-DQ - Structure, Functions, Genetics - Genetics - Effects of Heterogeneity of Isoform Pairing
... In coeliac disease, certain homozygotes and are at higher risk for disease and some specific complications of coeliac disease such as Gluten-sensitive enteropathy associated T-cell ... Homozygotes at DQ loci can change risk for disease. 2 copies of the DQ-like Iab haplotype are more likely to progress toward fatal disease compared to mice that are heterozygotes only for the beta allele (MHC IAαb / IAαb, IAβb / IAβbm12) ...
Gluten Immunochemistry - Innate Immunity - Alpha Gliadin 31-43 - Intraepithileal Lymphocytes and IL15
... The release of IL15 is a major factor in coeliac disease as IL15 has been found to attract intraepithelial lymphocytes (IEL) that characterize Marsh ... two ways the innate peptide activation of T-cells in celiac disease is strange ... In addition, innate immunity to IRP peptide is involved in coeliac disease, dermatitis herpetiformis and possibly juvenile diabetes ...
Coeliac Disease - History
9500 BCE) in the Fertile Crescent in Western Asia, and it is likely that coeliac disease did not occur before this time ... His "Cœliac Affection" (coeliac from Greek κοιλιακός koiliakos, "abdominal") gained the attention of Western medicine when Francis Adams presented a translation of Aretaeus's work ... malodorous and flatulent, and the disease was intractable and liable to periodic return ...
Samuel Gee - Coeliac Disease
... Samuel Gee gave the first modern-day description of coeliac disease in a lecture at the Hospital for Sick Children, Great Ormond Street in 1887 ... Signs of the disease are yielded by the fæces being loose, not formed, but not watery more bulky than the food taken would seem to account for pale in colour, as if devoid of bile ... Gee acknowledges earlier findings and terms for the disease and adopts the same term as Aretaeus ...

Famous quotes containing the word disease:

    In a country where misery and want were the foundation of the social structure, famine was periodic, death from starvation common, disease pervasive, thievery normal, and graft and corruption taken for granted, the elimination of these conditions in Communist China is so striking that negative aspects of the new rule fade in relative importance.
    Barbara Tuchman (1912–1989)