Issue
| Name | Birth | Death | Notes |
|---|---|---|---|
| Margaret | unknown | bef.11 Sep 1583 | married Thomas Wodehouse (or Woodhouse) |
| John | 1500 | November 1558 | 22nd Lord of Shelton, married Margaret Parker, older sister to Jane, Viscountess Rochford |
| Mary | unknown | 8 Jan 1570/1 | firstly married Sir Anthony Heveningham; secondly married Philip Appleyard; mistress of Henry VIII during 1535 |
| Ralph | unknown | 26 Sep 1561 | married Amy Wodehouse or Woodhouse (sister of Thomas, who married Margaret Shelton) |
| Thomas | unknown | aft 1579 | married Anne Appleyard |
| Anne | c. 1505 | 1563 | firstly married Edmund Knyvet; secondly married Christopher Coote, Esq. |
| Gabriella | unknown | Oct 1558 | died without issue |
| Elizabeth | unknown | aft 1561 | died without issue |
| Amy | unknown | November 1579 | died without issue |
| Emma | unknown | aft.1556 | died without issue |
Read more about this topic: Anne Shelton (courtier)
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—William Shakespeare (1564–1616)