History
Since 2000, light scattering systems have been used for biomedical applications such as the study of cellular morphology as well as the diagnosis of dysplasia. Variations in scattering distributions as a function of angle or wavelength have been used to deduce information regarding the size of cells and subcellular objects such as nuclei and organelles. These size measurements can then be used diagnostically to detect tissue changes—including neoplastic changes (those leading to cancer).
Light scattering spectroscopy has been used to detect dysplasia in the colon, bladder, cervix, and esophagus of human patients. Light scattering has also been used to detect Barrett’s esophagus, a metaplastic condition with a high probability of leading to dysplasia.
However, in contrast with a/LCI, these techniques all rely on total intensity based measurements, which lack the ability to provide results as a function of depth in the tissue.
Read more about this topic: Angle-resolved Low-coherence Interferometry
Famous quotes containing the word history:
“The foregoing generations beheld God and nature face to face; we, through their eyes. Why should not we also enjoy an original relation to the universe? Why should not we have a poetry and philosophy of insight and not of tradition, and a religion by revelation to us, and not the history of theirs?”
—Ralph Waldo Emerson (1803–1882)
“History ... is, indeed, little more than the register of the crimes, follies, and misfortunes of mankind.
But what experience and history teach is this—that peoples and governments have never learned anything from history, or acted on principles deduced from it.”
—Georg Wilhelm Friedrich Hegel (1770–1831)
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—Zora Neale Hurston (1891–1960)