Anaplastic Large-cell Lymphoma - Treatment

Treatment

  • Managed under "Aggressive Lymphoma" guidelines.
    • CHOP is first line of treatment, CHOP-Rituxan in the unlikely scenario that CD20 is positive, given that CD20 is a B-cell marker.
    • Radiation therapy as per institutional preference (based on ECOG, SWOG, and GELA trials), but usually added for bulky disease
  • Localized primary cutaneous ALCL
    • Radiation therapy alone
    • Surgical excision alone
    • Surgically excision with adjuvant radiation.

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