Anaplasma Phagocytophilum - Laboratory Diagnosis

Laboratory Diagnosis

Three tests can be performed to determine an A. phagocytophilum infection:

  1. Indirect immunofluorescence assay is the principal test used to detect infection. The acute and convalescent phase serum samples can be evaluated to look for a four-fold change in antibody titer to A. phagocytophilum.
  2. Intracellular Inclusions (morulae) are visualized in granulocytes on Wright- or Giemsa- stained blood smears.
  3. Polymerase chain reaction assays are used to detect A. phagocytophilum DNA.

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