Laboratory Diagnosis
Three tests can be performed to determine an A. phagocytophilum infection:
- Indirect immunofluorescence assay is the principal test used to detect infection. The acute and convalescent phase serum samples can be evaluated to look for a four-fold change in antibody titer to A. phagocytophilum.
- Intracellular Inclusions (morulae) are visualized in granulocytes on Wright- or Giemsa- stained blood smears.
- Polymerase chain reaction assays are used to detect A. phagocytophilum DNA.
Read more about this topic: Anaplasma Phagocytophilum
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