Amygdalin - Laetrile

Amygdalin is sometimes confused with laevomandelonitrile, also called laetrile for short; however, amygdalin and laetrile are different chemical compounds. Laetrile, which was patented in the United States, is a semi-synthetic molecule sharing part of the amygdalin structure, while the "laetrile" made in Mexico is usually amygdalin, the natural product obtained from crushed apricot pits, or neoamygdalin.

Laetrile has a melting point of 214 to 216 degrees Celsius. Its Chemical Abstracts Service Registry Number is 1332-94-1 and its International Union of Pure and Applied Chemistry nomenclature name is (2S,3S,4S,5R,6R)-6--3,4,5-trihydroxyoxane-2-carboxylic acid. Laetrile's chemical formula is C14H15NO7 and its PubChem number is 5484354. Its molecular weight is 309.2714 grams/mole. Laetrile is also classified as a cyanogenic glycoside.

Though it is sometimes sold as "Vitamin B17", it is not a vitamin. Amygdalin/laetrile was claimed to be a vitamin by chemist Ernst T. Krebs in the hope that if classified as a nutritional supplement it would escape the federal legislation regarding the marketing of drugs. He could also capitalise on the public fad for vitamins at that time.

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