Examples and Structure
Four structural classes of ampakine drugs have been developed so far:
- the pyrrolidine derivative racetam drugs such as piracetam and aniracetam
- the CX- series of drugs which encompass a range of benzoylpiperidine and benzoylpyrrolidine structures
- benzothiazide derivatives such as cyclothiazide and IDRA-21
- biarylpropylsulfonamides such as LY-392,098, LY-404,187, LY-451,646 and LY-503,430
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