Alternatives To Animal Testing - Origin

Origin

In 1954, Charles Hume, founder of the Universities Federation for Animal Welfare (UFAW) made an original proposal for the Three Rs to the UFAW to take in consideration alternatives for animal testing and change scientific study in laboratory animal experiments. Committee under the chairmanship of Sir Peter Medawar, the Nobel prize-winning immunologist, along with Christine Stevens, founder of the Animal Welfare Institute (AWI) in the U.S, and William Lane-Petter, the Secretary of the Research Defense Society of Great Britain provided financial support and managed the project to publish the concept of animal testing alternatives. The microbiologist R.L. Burch and the zoologist W.M.S. Russell were chosen to publish the work. "The Principles of Humane Experimental Technique" was published in London in 1959, and the book defined animal testing alternatives as “The Three R's: Refinement, Reduction, and Replacement.”

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