Almagro may refer to:
- Diego de Almagro (1475–1538), Spanish explorer
- Diego Almagro II (1520–1542), assassin of Spanish conquistador Francisco Pizarro
- Nicolás Almagro (born 1985), Spanish tennis player
- Almagro, Buenos Aires
- Almagro, Ciudad Real, Castile-La Mancha, Spain
- Almagro, Samar, municipality of the Samar province in Philippines
- Club Almagro, an Argentine football club from Almagro, Buenos Aires
- Estadio Almagro, a multi-use stadium in Buenos Aires, Argentina
- Diego de Almagro Island