Education
Middendorff received his early education from tutors in Reval and at a gymnasium in Saint Petersburg. From 1832 he pursued a medical degree at the Imperial University of Dorpat where his professors included Georg Friedrich Parrot, Nikolay Ivanovich Pirogov, Hermann Martin Asmuss, and Alexander Friedrich von Hueck. Middendorff graduated in 1837 with a dissertation (written in Latin) on polyps in the bronchi. He then undertook further studies at the Humboldt University of Berlin, University of Erlangen-Nuremberg, University of Vienna, and University of Breslau. In 1839, under the patronage of Karl Ernst von Baer, he accepted a job at Kiev University.
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