Akathisia - Treatment

Treatment

Akathisia can be reduced by withdrawing or decreasing the dose of the causative agent, or by administering other drugs, though the latter proves many times to be counter-productive unless the person administering and managing the drugs has an extensive knowledge of neurobiology and pharmacokinetics. The first-line treatment of akathisia is usually propranolol. Benzodiazepines such as clonazepam are also effective to a certain degree. Benztropine, procyclidine and trihexyphenidyl can also be used.

One study showed that vitamin B6 is effective for the treatment of neuroleptic-induced akathisia.

N-acetyl cysteine also showed a positive effect on akathisia in an RCT.

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