Notable Alumnae
- Nathalie Anderson ’70, poet and author of Following Fred Astaire
- Osjha Anderson Domenicone ’96, Miss Georgia 1999
- Ruth Janet Pirkle Berkeley ’22, one of the nation’s first women psychiatrists
- Margaret Booth (Agnes Scott Institute, d.), educational and cultural mentor for the Montgomery, Alabama area; Inducted into the Alabama Women's Hall of Fame posthumously in 1999
- Sammye Burnett Brown ’68, the first woman president of the Georgia Association of Psychiatrists
- Mary Brown Bullock ’66, president emerita and only alumna to serve as president of the college
- Ila Burdette ’81, Georgia's first female Rhodes scholar
- Dorothy Cave ’49, prominent New Mexico author and historian
- Faith Yao Yu Chao ’61, founder and director of the Evergreen Educational Foundation, a recent Bill and Melinda Gates foundation award winner
- Carolyn Crawford Chesnutt ’55, served as executive director of the Southeast Consortium of Minorities in Engineering
- Georgia B. Christopher ’55, served as president of the Milton Society in 1986
- Constance W. Curry ’55, civil rights activist and author of the award-winning Silver Rights
- Ann Crichton ’61, served as first woman mayor of Decatur, Georgia and representative of the state of Kentucky’s interests in Great Britain
- Laura Dorsey ’66x, hospital chaplain, author and founder of Gardens for Peace, an international organization which designates gardens as places of meditation and a symbol of peace
- Susie Goodman Elson ’59, served as president of the National Mental Health Association
- Daphne Faulkner ’83, religious and political activist, founder and first president of the Georgia chapter of People of Faith for the ERA
- Mamie Lee Ratliff Finger ’39, president of the foundation that funds Ewha Women's University in Seoul, Korea, the largest women's university in the world
- Carolyn Essig Friedrich ’22, the first woman elected to represent the upstate in the South Carolina House of Representatives in 1966
- Margot Gayle ’31x, American historic preservationist and author who helped save the Victorian cast-iron architecture in New York City's SoHo district
- Karen Gearreald ’66, Agnes Scott's first blind student, who answered the final question to beat Princeton (see above) and was named Outstanding Alumna for Distinguished Career in 1997
- Mary Duckworth Gellerstedt ’46, the first woman president of the Atlanta Symphony Board of Directors who was also named Atlanta Volunteer of the Year in 1986
- Sophie Haas Gimble ’1912, fashion designer and merchandiser at Saks Fifth Avenue who appeared on the cover of Time magazine in 1947
- Elizabeth Riseley Griffin ’97, a biology student whose death after contracting the B virus while working with Rhesus macaques at the Yerkes Regional Primate Research Center led to the creation of a memorial foundation and legislation governing primate research safety in the United States
- Katherine Harris ’79, former Florida Secretary of State and U.S. Representative
- Rachelle Henderlite ’28 (d.), the first woman to be ordained a minister in the Presbyterian Church (USA)
- Bertha "B" Holt ’38 (d.), former North Carolina State Representative and children's rights advocate
- Amy Kim ’97, winner of the 2007 Academy Award for "Best Live Action Short Film" for her work as a producer on West Bank Story
- Katherine "Kay" Krill ’77, CEO of Ann Taylor
- Michelle Malone ’90x, musician
- Catherine Marshall ’36, author of the novel Christy, later made into a TV series and A Man Called Peter
- Joanna Cook Moore, actress and mother of Tatum O'Neal
- Jennifer Nettles ’97, Lead singer of the AMA and Grammy award winning country music band Sugarland
- Frances Newman (Agnes Scott Institute, d.), first librarian of Atlanta's Carnegie Library and celebrated feminist novelist, author of The Hard-Boiled Virgin, Dead Lovers are Faithful Lovers, and The Gold-Fish Bowl
- Marsha Norman ’69x, playwright
- Evangeline Thomas Papageorge ’28, the first woman full-time manager at Emory University School of Medicine
- Jessica Daves Parker ’1914, editor in chief of Vogue magazine 1952-1962
- Susan Philips ’67, the first woman to chair a financial regulatory agency (the Commodity Futures Trading Commission)
- Carolyn Forman Piel ’40, elected in 1986, she is the first female president of the American Academy of Pediatrics
- Margaret Evans Porter ’80, romance novelist
- Mia Puckett ’86, first female, black District Attorney in the state of Alabama, currently state director of human resources
- Jeanne Addison Roberts ’47, served as president of the Shakespeare Society of America in 1986
- Louise Röska-Hardy ’72, Phi Beta Kappa, philosopher specializing in philosophy of language and of mind
- Agnes White Sanford ’19x, author of the book The Healing Light
- Saycon Sengbloh ’00x, Broadway star and recording artist
- Pris Shepperd Taylor ’58, served as editor of the Phi Beta Kappa journal
- Jean H. Toal ’65, Chief Justice of the South Carolina Supreme Court
- M. Virginia Tuggle ’44, the first woman on the Georgia State Board of Medical Examiners
- Leila Ross Wilburn ’1904, Architect
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—For the State of Florida, U.S. public relief program (1935-1943)