Other
- Acronym Fatigue Syndrome
- Active Front Steering, vehicle steering technology similar to Active Steering
- Adaptive Front-light System, Device to optimal vehicle illumination
- Aeronautical Fixed Service, telecommunication service for the safety of air navigation
- AFS Trinity Power Corporation, an American company that develops hybrid vehicle technology
- Allergic fungal sinusitis, an inflammatory condition of the paranasal sinuses
- Alliance for Security, an American political organization founded in 2004
- American Folklore Society, the scholarly association of all folklorists in the United States
- Amniotic fluid-derived stem, a type of stem cell
- Anti-funnel System, a Newtype technology in the manga Mobile Suit Gundam REON
- Arch filament system
- Armor for Sleep, an American rock band
- Ashford (Surrey) railway station, a railway station located in Ashford, Middlesex, United Kingdom
- Association of Football Statisticians, a British football (soccer) statistical organisation
- Atomic fluorescence spectroscopy, a common version of spectroscopy in the range of UV-light
- Australian Flag Society, an Australian patriotic society founded in 2003
- Automatic Frequency Switch, a system that is comparable with RDS function for radio
- Auxiliary Fire Service, a service active in the UK during the periods of 1938-1942 & 1948-1968 and still active in Ireland
- Available for sale, a type of financial asset
- Nikon AF-S, designation for "silent wave" internal motor Nikon AF lenses
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