ADC may refer to:
In aviation:
- ADC Aircraft, a British firm established in March 1920
- ADC Airlines, based in Ikeja, Nigeria
- Aerospace Defense Command of the U.S. Air Force
- Air data computer
In biology and medicine:
- ADC (gene), a human gene
- ADC Bioscientific, a British company which manufactures equipment for research into plant physiology
- AIDS dementia complex, a common neurological disorder associated with HIV infection and AIDS
- Antibody-drug conjugate, a type of anticancer treatment
- Automated dispensing cabinet, a computerized drug storage device designed for hospitals
In entertainment and the arts:
- ADC Theatre, venue of the University of Cambridge Amateur Dramatic Club
- Australian Dance Council, a national dance advocacy organisation
In government and politics:
- Aid to Dependent Children, an American government social program from 1935–1960
- American Deserters Committee, an anti-Vietnam War group
- American-Arab Anti-Discrimination Committee, a civil rights organization
- Arizona Department of Corrections
- The Asociación Democrática de Colima, a political party from the State of Colima, Mexico
In technology:
- ADC Telecommunications in Eden Prairie, Minnesota
- Advanced Data Connector, a Microsoft technology used in conjunction with ActiveX Data Objects
- Advanced Direct Connect, a peer-to-peer file sharing and chat protocol
- Analog-to-digital converter, an electronic circuit that converts continuous signals to discrete digital numbers
- Android Developer Challenge, a competition
- Apple Developer Connection, Apple Computer's developer network
- Apple Display Connector, a proprietary modification of the DVI connector
- Application Delivery Controller, a device for accelerating web site performance
- Armenian Datacom Company, in Yerevan, Armenia
In other fields:
- Acadia Divinity College, a seminary located on the campus of Acadia University
- ADC Map, an American publisher of maps and street atlases
- Adlington (Cheshire) railway station's (British) National Rail code
- After-death communications, the pseudo science alleging communications from a person who has died
- Aide-de-camp, a personal assistant, secretary, or adjutant to a person of high rank
- Andrew Dice Clay, an American comedian
- Australian Defence College, located at Weston Creek in Canberra
- CR-39, also known as allyl diglycol carbonate