Actin, Alpha 1

Actin, Alpha 1

Identifiers Symbols ACTA1; ACTA; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3 External IDs OMIM: 102610 MGI: 87902 HomoloGene: 121702 GeneCards: ACTA1 Gene

Gene Ontology
Molecular function structural constituent of cytoskeleton
protein binding
ATP binding
myosin binding
ADP binding
Cellular component stress fiber
cytosol
striated muscle thin filament
actin filament
actin cytoskeleton
sarcomere
extracellular vesicular exosome
Biological process muscle contraction
response to mechanical stimulus
response to extracellular stimulus
response to lithium ion
cell growth
muscle filament sliding
skeletal muscle thin filament assembly
skeletal muscle fiber adaptation
response to steroid hormone stimulus
skeletal muscle fiber development
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 58 11459 Ensembl ENSG00000143632 ENSMUSG00000031972 UniProt P68133 P68134 RefSeq (mRNA) NM_001100 NM_001272041 RefSeq (protein) NP_001091 NP_001258970 Location (UCSC) Chr 1:
229.57 – 229.57 Mb Chr 8:
123.89 – 123.89 Mb PubMed search

Actin, alpha skeletal muscle is a protein that in humans is encoded by the ACTA1 gene.

Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.

Read more about Actin, Alpha 1:  Skeletal Actin Gene Expression, Interactions

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