Acetylcholine - Drugs Acting On The Cholinergic System

Drugs Acting On The Cholinergic System

Blocking, hindering or mimicking the action of acetylcholine has many uses in medicine. Drugs acting on the acetylcholine system are either agonists to the receptors, stimulating the system, or antagonists, inhibiting it.

ACh and its receptors
Drug Nm Nn M1 M2 M3
ACh, Charbacol, AChEi (Physostigmine, Galantamine, Neostigmine, Pyridostigmine) + + + + +
Nicotine, Varenicline + +
Succinylcholine +/-
Atracurium, Vecuronium, Tubocurarine, Pancuronium -
Epibatidine, DMPP +
Trimethaphan, Mecamylamine, Bupropion, Dextromethorphan, Hexamethonium -
Muscarine, Methacholine, Oxotremorine, Bethanechol, Pilocarpine + + +
Atropine, Tolterodine, Oxybutynin - - -
Vedaclidine, Talsaclidine, Xanomeline, Ipatropium +
Pirenzepine, Telenzepine -
Methoctramin -
Darifenacin, 4-DAMP, Darifenacin, Solifenacin -

Read more about this topic:  Acetylcholine

Famous quotes containing the words drugs, acting and/or system:

    There is not much sense in suffering, since drugs can be given for pain, itching, and other discomforts. The belief has long died that suffering here on earth will be rewarded in heaven. Suffering has lost its meaning.
    Elisabeth Kübler-Ross (b. 1926)

    If you are willing to inconvenience yourself in the name of discipline, the battle is half over. Leave Grandma’s early if the children are acting impossible. Depart the ballpark in the sixth inning if you’ve warned the kids and their behavior is still poor. If we do something like this once, our kids will remember it for a long time.
    Fred G. Gosman (20th century)

    I have no concern with any economic criticisms of the communist system; I cannot enquire into whether the abolition of private property is expedient or advantageous. But I am able to recognize that the psychological premises on which the system is based are an untenable illusion. In abolishing private property we deprive the human love of aggression of one of its instruments ... but we have in no way altered the differences in power and influence which are misused by aggressiveness.
    Sigmund Freud (1856–1939)