Abiraterone - History

History

In the early 1990s, Mike Jarman, Elaine Barrie and Gerry Potter of the Cancer Research UK Centre for Cancer Therapeutics within the Institute of Cancer Research in London set out to develop drug treatments for prostate cancer. Starting from the drug ketoconazole, they developed abiraterone as a more effective variant, filing a patent in 1993 and publishing the first paper describing the drug the following year. Rights for commercialisation of the drug were assigned to BTG plc, a UK-based specialist healthcare company. BTG then licenced the product to Cougar Biotechnology which began development of the commercial product. In 2009, Cougar was acquired by Johnson & Johnson which developed and sells the commercial product, and is conducting ongoing clinical trials to expand its clinical uses.

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