Abacavir/lamivudine/zidovudine

Abacavir/lamivudine/zidovudine (INNs, trade name Trizivir) is a pharmaceutical treatment for HIV infection. It is a fixed dose combination of three reverse transcriptase inhibitors patented by GlaxoSmithKline and now marketed by its joint venture with Pfizer, ViiV Healthcare:

  • abacavir ("ABC")
  • lamivudine ("3TC")
  • zidovudine ("AZT")

It is indicated in the treatment of AIDS/HIV.

The combination of drugs helps to reduce HIV's resistance (through mutation) to the drugs individually. Of the three, AZT and ABC have passed out of United States patent protection.