Schedule
| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| August 30 | 8:00 PM | vs. Alabama* | #9 | Georgia Dome • Atlanta, GA (Chick-fil-A College Kickoff) | ABC | L 10–34 | 70,097 | |
| September 6 | 3:30 PM | The Citadel* | #22 | Memorial Stadium • Clemson, SC (Military Appreciation Day) | W 45–17 | 76,794 | ||
| September 13 | 12:00 PM | NC State | #23 | Memorial Stadium • Clemson, SC (Textile Bowl/Hall of Fame Day) | Raycom | W 27–9 | 77,071 | |
| September 20 | 1:00 PM | SC State* | #21 | Memorial Stadium • Clemson, SC (Youth Day) | W 54–0 | 78,607 | ||
| September 27 | 12:00 PM | Maryland | #19 | Memorial Stadium • Clemson, SC (Family Weekend) | Raycom | L 17–20 | 81,500 | |
| October 9 | 7:45 PM | at Wake Forest | BB&T Field • Winston-Salem, NC | ESPN | L 7–12 | 33,988 | ||
| October 18 | 12:00 PM | Georgia Tech | Memorial Stadium • Clemson, SC (IPTAY Day) | ESPN | L 17–21 | 81,500 | ||
| November 1 | 3:30 PM | at Boston College | Alumni Stadium • Chestnut Hill, MA (O'Rourke-McFadden trophy) | ESPNU | W 27–21 | 41,863 | ||
| November 8 | 3:30 PM | at #24 Florida State | Doak Campbell Stadium • Tallahassee, FL | ABC | L 27–41 | 77,013 | ||
| November 15 | 12:00 PM | Duke | Memorial Stadium • Clemson, SC (Homecoming) | Raycom | W 31–7 | 76,217 | ||
| November 22 | 12:00 PM | at Virginia | Scott Stadium • Charlottesville, VA | Raycom | W 13–3 | 51,979 | ||
| November 29 | 12:00 PM | South Carolina* | Memorial Stadium • Clemson, SC (Battle for the Palmetto State/Solid Orange Game) | ESPN2 | W 31–14 | 82,456 | ||
| January 1, 2009 | 1:00 PM | vs. Nebraska* | Jacksonville Municipal Stadium • Jacksonville, FL (Gator Bowl) | CBS | L 21–26 | 67,282 | ||
Read more about this topic: 2008 Clemson Tigers Football Team