Schedule
| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| September 2 | 1:00 PM | Indiana State* | Ross–Ade Stadium • West Lafayette, IN | W 60–35 | 50,108 | |||
| September 9 | 1:00 PM | Miami (OH)* | Ross–Ade Stadium • West Lafayette, IN | ESPN360 | W 38–31 OT | 53,668 | ||
| September 16 | 1:00 PM | Ball State* | Ross–Ade Stadium • West Lafayette, IN | ESPN360 | W 38–28 | 51,561 | ||
| September 23 | 12:00 PM | Minnesota | Ross–Ade Stadium • West Lafayette, IN | ESPN2 | W 27–21 | 54,620 | ||
| September 30 | 2:30 PM | at #14 Notre Dame* | Notre Dame Stadium • Notre Dame, IN | NBC | L 21–35 | 80,795 | ||
| October 7 | 12:00 PM | at #19 Iowa | Kinnick Stadium • Iowa City, IA | ESPNU | L 17–47 | 70,585 | ||
| October 14 | 12:00 PM | at Northwestern | Ryan Field • Evanston, IL | ESPN+ | W 31–10 | 27,171 | ||
| October 21 | 12:00 PM | #22 Wisconsin | Ross–Ade Stadium • West Lafayette, IN | ESPN | L 3–24 | 58,111 | ||
| October 28 | 12:00 PM | Penn State | Ross–Ade Stadium • West Lafayette, IN | ABC | L 0–12 | 58,025 | ||
| November 4 | 3:30 PM | at Michigan State | Spartan Stadium • East Lansing, MI | ESPNU | W 17–15 | 65,398 | ||
| November 11 | 12:00 PM | at Illinois | Memorial Stadium • Champaign, IL (Purdue Cannon) | ESPN+ | W 42–31 | 44,266 | ||
| November 18 | 12:00 PM | Indiana | Ross-Ade Stadium • West Lafayette, IN (Old Oaken Bucket) | ESPNC | W 28–19 | 62,105 | ||
| November 25 | 11:00 PM | at #25 Hawaii* | Aloha Stadium • Honolulu, HI | L 35–42 | 47,825 | |||
| December 29 | 8:00 PM | vs. Maryland* | Citrus Bowl • Orlando, FL (Champs Sports Bowl) | ESPN | L 7–24 | 40,168 | ||
Read more about this topic: 2006 Purdue Boilermakers Football Team