Preseason
| Game | Date | Opponent | Result | Lions points | Opponents |
| 1 | August 4 | New England Patriots | Loss | 10 | 13 |
| 2 | August 12 | Buffalo Bills | Win | 15 | 13 |
| 3 | August 18 | at Oakland Raiders | Loss | 17 | 23 |
| 4 | August 25 | at Cincinnati Bengals | Win | 21 | 13 |
Read more about this topic: 2000 Detroit Lions Season