Offseason
- October 23, 1980: Randy Elliott was released by the Athletics.
- December 8, 1980: Brian Doyle was drafted by the Athletics from the New York Yankees in the 1980 rule 5 draft.
- December 9, 1980: DeWayne Buice was drafted by the Oakland Athletics from the San Francisco Giants in the 1980 minor league draft.
- December 11, 1980: Michael King (minors) was traded by the Athletics to the Chicago Cubs for Cliff Johnson and Keith Drumright.
- January 13, 1981: Steve Kiefer was drafted by the Athletics in the 1st round of the 1981 Major League Baseball Draft.
- February 10, 1981: The Athletics traded a player to be named later to the Houston Astros for Jimmy Sexton. The Athletics completed the trade by sending Rick Lysander to the Astros on October 20.
- March 27, 1981: Bob Lacey and Roy Moretti (minors) were traded by the Athletics to the San Diego Padres for Kevin Bell, Tony Phillips and Eric Mustad (minors).
- March 30, 1981: Alan Wirth was released by the Athletics.
Read more about this topic: 1981 Oakland Athletics Season