Offseason
- December 8, 1980: Dave Edwards was traded by the Twins to the San Diego Padres for Chuck Baker.
- December 8, 1980: Jack O'Connor was drafted by the Twins from the Montreal Expos in the rule 5 draft.
- December 12, 1980: Willie Norwood was traded by the Twins to the Seattle Mariners for Byron McLaughlin.
- March 27, 1981: Bombo Rivera was released by the Twins.
- March 30, 1981: Ken Landreaux was traded by the Twins to the Los Angeles Dodgers for Mickey Hatcher, Kelly Snider (minors), and Matt Reeves (minors).
Read more about this topic: 1981 Minnesota Twins Season