Schedule
| Week | Date | Opponent | Result | Attendance |
|---|---|---|---|---|
| 1 | September 6, 1981 | San Francisco 49ers | W 24-17 |
|
| 2 | September 13, 1981 | at San Diego Chargers | L 28-23 |
|
| 3 | September 20, 1981 | at Minnesota Vikings | L 26-24 |
|
| 4 | September 27, 1981 | Oakland Raiders | W 16-0 |
|
| 5 | October 4, 1981 | at Tampa Bay Buccaneers | L 28-10 |
|
| 6 | October 11, 1981 | at Denver Broncos | L 27-21 |
|
| 7 | October 19, 1981 | Chicago Bears | W 48-17 |
|
| 8 | October 25, 1981 | Green Bay Packers | W 31-27 |
|
| 9 | November 1, 1981 | at Los Angeles Rams | L 20-13 |
|
| 10 | November 8, 1981 | at Washington Redskins | L 33-31 |
|
| 11 | November 15, 1981 | Dallas Cowboys | W 27-24 |
|
| 12 | November 22, 1981 | at Chicago Bears | W 23-7 |
|
| 13 | November 26, 1981 | Kansas City Chiefs | W 27-10 |
|
| 14 | December 6, 1981 | at Green Bay Packers | L 31-17 |
|
| 15 | December 12, 1981 | Minnesota Vikings | W 45-7 |
|
| 16 | December 20, 1981 | Tampa Bay Buccaneers | L 20-17 |
|
Read more about this topic: 1981 Detroit Lions Season