Quarter-Finals
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| JE Tizi-Ouzou | 3-3 | AS Vita Club | 3-2 | 0-1 |
| Canon Yaoundé | 3-1 | Green Buffaloes | 2-0 | 1-1 |
| Enugu Rangers | 4-1 | Kampala City Council | 3-1 | 1-0 |
| Silures | 1-8 | Hafia FC | 0-4 | 1-4 |
Read more about this topic: 1978 African Cup Of Champions Clubs