Offseason
- October 3, 1949: Ralph Winegarner was released by the Browns.
- December 5, 1949: Grant Dunlap was drafted by the Browns from the Cleveland Indians in the 1949 minor league draft.
- December 13, 1949: Bob Dillinger and Paul Lehner were traded by the Browns to the Philadelphia Athletics for Ray Coleman, Billy DeMars, Frankie Gustine, Ray Ippolito (minors) and $100,000.
- Prior to 1950 season: Bud Black was signed as an amateur free agent by the Cardinals.
Read more about this topic: 1950 St. Louis Browns Season