1935 in Science - Pharmacology

Pharmacology

• January 2 - IG Farben are granted a patent in Germany for the medical application of the first sulfonamide prodrug, Sulfonamidochrysoidine (KI-730; marketed as Prontosil). In February, Gerhard Domagk and others publish (in Deutsche Medizinische Wochenschrift) the first clinical results on its properties as an antibiotic, the first commercially available; and in November a team directed by Ernest Fourneau at the Pasteur Institute identify sulfanilamide as the active component.