17-beta-hydroxysteroid Dehydrogenase Deficiency - Biochemistry

Biochemistry

17β-Hydroxysteroid dehydrogenase III deficiency is characterized biochemically by decreased levels of testosterone and increased levels of androstenedione as a result of the defect in conversion of androstenedione into testosterone. This leads to clinically important higher ratio of androstenedione to testosterone (A'dion/T) (see figure).

Read more about this topic:  17-beta-hydroxysteroid Dehydrogenase Deficiency