Function
1-phosphofructokinase catalyzes the committed step of glycolysis. This step is considered the rate limiting step of glycolysis, and ultimately determines the rate of glucose oxidation in the cell. This reaction is a phosphoryl group transfer from ATP to fructose 6-phosphate, yielding fructose 1,6-biphosphate. The reaction is highly exergonic and is irreversible within the cell, though can be bypassed in gluconeogenesis via the enzyme fructose 1,6-bisphosphatase.
Read more about this topic: 1-phosphofructokinase
Famous quotes containing the word function:
“The art of living is to function in society without doing violence to one’s own needs or to the needs of others. The art of mothering is to teach the art of living to children.”
—Elaine Heffner (20th century)
“The function of comedy is to dispel ... unconsciousness by turning the searchlight of the keenest moral and intellectual analysis right on to it.”
—George Bernard Shaw (1856–1950)
“The function of the actor is to make the audience imagine for the moment that real things are happening to real people.”
—George Bernard Shaw (1856–1950)